Researchers say they’ve developed the world’s first reliable blood test to detect myalgic encephalomyelitis, or chronic fatigue syndrome (ME/CFS).
Led by Prof Dmitry Pshezhetskiy at the University of East Anglia, the study found distinctive DNA-folding patterns in ME/CFS patients’ blood.
Using samples from 47 patients and 61 healthy adults, the test showed 92% sensitivity and 98% specificity.
“This could transform diagnosis and management,” Pshezhetskiy said. “For the first time, we have a simple, accurate test.”
The research, published in The Journal of Translational Medicine, was co-authored by Oxford Biodynamics, which funded the study.
Experts welcomed the findings but urged caution. “It’s an important step, but more independent studies are needed,” said Dr Charles Shepherd of the ME Association.
Prof Chris Ponting warned the claims were “premature,” saying the test must be validated further and could cost around £1,000.
If confirmed, the breakthrough could end years of uncertainty for ME/CFS patients often dismissed or misdiagnosed.
